Description
TPGS stands for Tocopheryl Polyethylene Glycol 1000 Succinate. It is a water-soluble, nonionic vitamin E derivative. TPGS is derived from natural vitamin E and modified to improve its solubility in aqueous systems. It is commonly available in the form of yellow to light brown powder.
Function
TPGS has several important functions in various industries. Firstly, it acts as a solubilizer and emulsifier, helping to enhance the solubility and stability of poorly water-soluble drugs and nutraceuticals in aqueous environments. Secondly, TPGS exhibits excellent antioxidant properties, which can protect sensitive compounds from oxidation and degradation. Additionally, TPGS has been found to enhance drug absorption through various mechanisms, including inhibition of efflux transporters and improvement of mucosal permeability.
Application
Medicinal Field:
It is mainly used as excipient and absorption enhancer. Due to its emulsifying and solubilizing effects, it can effectively improve the bioavailability of drugs. Thus, it can reduce the amount of drug use and reduce the toxic side effects of drugs.
1. Anti-tumor drug: FDA approved paclitaxel emulsion formulation (Sonus Pharmaceuticals)
2. Anti-HIV drugs: Agenerase (Amprenavir) and APTIVUS (Telanavir).
3. Anti-hepatitis C virus (HCV) drugs: VIEKERA Pack tablets.
4. Ophthalmic medications: dry eye; prevention of contact lens wear; healing of the postoperative cornea.
5. Treatment of vitamin E deficiency caused by chronic bile deficiency.
Food and Cosmetics Field:
1. Converts a wide range of natural nutrients into stable, water-soluble liquids or powders.
2. Has antioxidant and anti-aging effects.
Our products are registered with USDMF.
1.Are you manufacturer or trading company?
A:We are manufacturer and welcome to visit our factory.
2.How to confirm the product quality before place an order?
A:We can provide you with sample .Also we have the inspection report issued by the authoritative third- party testing agency.
3: What's your MOQ?
A:It's depend on different products. We accept sample order. Also for some products we can provide you with free sample.
4:Do you provide after sales service?
A:We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us.
5:How about delivery time and method?
A:We usually shipping within 3-5 working days after payments.
We can shipping by sea, air and express. Also can make door to door shipping.
6:How to solve the after-sale disputes?
A: We accept changing or refunding service if any quality problem.