Customization: | Available |
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Function: | Nutritional Supplements |
Certification: | ISO, HACCP |
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Product Description:
Human Milk Oligosaccharides (HMOs) are complex, indigestible carbohydrates naturally abundant in human breast milk, representing the third-largest solid component after lactose and lipids. Structurally diverse, over 200 unique HMO structures are synthesized through enzymatic or microbial fermentation processes to replicate their natural profiles. These white to off-white, free-flowing powders exhibit high purity (>95%), water solubility, and stability across a wide pH range (3-8). Produced under cGMP and ISO standards, HMOs are non-GMO, allergen-free, and compliant with regulatory approvals (GRAS, EU Novel Food). Packaged in moisture-resistant, light-protective containers with nitrogen flushing, they maintain integrity for 24-36 months when stored at ≤25°C. Ideal for fortifying infant formulas, functional foods, and nutraceuticals, HMOs bridge the compositional gap between breast milk and synthetic nutritional products.
Function:
1. Prebiotic Activity:
Selectively stimulates growth of beneficial gut microbiota (e.g., Bifidobacteria, Lactobacillus), while inhibiting pathogens (e.g., E. coli, Campylobacter).
2. Immune System Modulation:
a. Mimics pathogen receptor sites, preventing microbial adhesion to intestinal epithelium (anti-adhesive effect).
b. Enhances secretion of anti-inflammatory cytokines (e.g., IL-10) and supports gut-associated lymphoid tissue (GALT) development.
3. Cognitive & Neurological Support:
a. Sialylated HMOs (e.g., 3′-SL, 6′-SL) contribute to brain development via sialic acid incorporation into neuronal gangliosides.
Gut Barrier Integrity:
b. Promotes mucin production and tight junction protein expression, reducing intestinal permeability ("leaky gut").
4. Metabolic Health:
Modulates host metabolism through microbial-derived short-chain fatty acid (SCFA) production.
5. Anti-Infective Properties:
Reduces risk of necrotizing enterocolitis (NEC) in preterm infants and diarrheal infections.
Applications:
1. Infant Nutrition:
a. Formula Fortification: Added to infant formulas to replicate breast milk's bioactivity, supporting immune and cognitive development (dosage: 1-2 g/L, mirroring human milk levels).
b. Premature Infant Care: Reduces NEC incidence in neonatal intensive care units (NICUs).
2. Maternal & Pediatric Health:
a. Prenatal/postnatal supplements to enhance maternal microbiota and vertical transmission of beneficial bacteria.
Adult Nutraceuticals:
b. Gut Health: Probiotic synbiotics for IBS, IBD, or antibiotic-associated dysbiosis management.
Immune Support: Functional ingredients in immunity-boosting supplements.
3. Medical Nutrition:
Enteral/parenteral nutrition for critically ill patients to prevent sepsis and gut atrophy.
4. Functional Foods & Beverages:
Added to yogurts, cereals, and sports drinks for prebiotic benefits without altering taste/texture.
5. Pharmaceuticals:
Adjuvant in oral vaccines to enhance mucosal immunity.
6. Research & Diagnostics:
Biomarkers in lactation studies or tools for investigating host-microbe interactions.
7. Veterinary Use:
Gut health promoters in livestock/pet feed to reduce antibiotic dependence.
Human Milk Oligosaccharides represent a groundbreaking advancement in precision nutrition, offering multifunctional benefits rooted in evolutionary biology. Their ability to shape the microbiome, fortify immunity, and support neurodevelopment positions HMOs as critical ingredients for next-generation infant formulas and beyond. By bridging the functional gap between synthetic and natural nutrition, HMOs empower innovation in pediatrics, clinical care, and preventive health, aligning with global trends toward personalized, microbiome-targeted wellness solutions.
1. Are you a manufacturer or trading companyA: We are a manufacturer and welcome to visit our factory.
2. How to confirm the product quality before place an order?
A: We can provide you with a sample. Also, we have the inspection report issued by the authoritative third-party testing agency.
3: What's your MOQ?
A: It depends on different products. We accept sample orders. Also, for some products, we can provide you with a free sample.
4: Do you provide after-sales service?
A: We provide 24-hour customer service. If you encounter any product quality problems or transportation problems, please feel free to contact us
5: How about delivery time and method?
A: We usually ship within 3-5 working days after payments.
We can ship by sea, air, and express. It also can make door-to-door shipping.
6: How to solve the after-sale disputes?
A: We accept changing or refunding service if any quality problem.