| Customization: | Available |
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| CAS No.: | 1197-18-8 |
| Formula: | C8h15no2 |
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Product Description
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Product Name
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Kojic Acid Dipalmitate
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Kojic Acid
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Molecular Formula
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618g/mol
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142g/mol
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Physical and chemical properties
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white crystalline powder,melting point 92-96ºC
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white to light yellow crystalline powder, melting point 150-154ºC
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Solubility
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Insoluble in water,soluble in Oil and glycol
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Easily soluble in water,Ethanol and
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PH Stability
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Stable when PH3-10
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Not stable when PH>7
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Color stability
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Does not chelate with metal ions, color is stable and does not change color
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Easily chelate and discolor with metal ions, turn yellow or brown
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Other Stability
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Good light stability, not easily oxidized
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Light, heat, and metal ions have poor stability and are easily oxidized
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Compounding performance
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Compatible with most makeup products
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Incompatible with some sunscreens, preservatives
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Tranexamic acid is a synthetic derivative of the amino acid lysine. Tranexamic acid (commonly marketed in tablet form as Lysteda and in IV form as Cyklokapron in the U.S. and as Transamin, Transcom in Asia, and Espercil in South America) is often prescribed for excessive bleeding.
Tranexamic acid is an antifibrinolytic that competitively inhibits the activation of plasminogen to plasmin, a molecule responsible for the degradation of fibrin. Fibrin is the basic framework for the formation of a blood clot in hemostasis. Tranexamic acid has roughly 8 times the antifibrinolytic activity of an older analog, ε-aminocaproic acid.
Function & Application
Tranexamic acid is frequently used in surgeries with a high risk of blood loss such as cardiac, liver, vascular, and large orthopedic procedures. Its oral form is now being evaluated for use in outpatient conditions involving heavy bleeding.
Trauma
Tranexamic acid has been found to decrease the risk of death in people who have significant bleeding due to trauma. However, it may actually increase the risk of death due to bleeding if administered more than 3 hours after the injury.
Heart surgery
Tranexamic acid is commonly used in cardiac surgery, both with and without cardiopulmonary bypass. It replaces aprotinin.
Orthopedic surgery
Tranexamic acid is used in orthopedic surgery to reduce blood loss. It is of proven value in clearing the field of surgery and reducing pre- and postoperative blood loss. Drain and number of transfusions are reduced.
Packaging & Shipping
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