| Function: | Disintegrant |
|---|---|
| Certification: | FDA |
| Grade Standard: | Medicine Grade |
| Type: | Chemical Reagent |
| State: | Solid |
| Volatile: | Not Volatile |
| Samples: |
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| Customization: |
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Audited Supplier Product Description
Crospovidone, also known as polyvinylpolypyrrolid or PVP-C, is a synthetic, water-insoluble polymer that is widely used in the pharmaceutical industry. It is a white, free-flowing that exhibits excellent swelling and binding properties.
Function
Crospovidone plays a crucial role as a disintegr in pharmaceutical formulations. Its main function is to promote the rapid breakup and dispersion of tablets or capsules in the gastrointestinal tract, facilitating the release of active ingredients for optimal absorption. It achieves this by absorbing water and swelling, leading to the disintegration of the dosage form.
Application
Crospovidone finds extensive application in the pharmaceutical industry as a pharmaceutical excipient. It is commonly used in the formulation of tablets, capsules, and other solid oral dosage forms. Its excellent disintegrating properties make it suitable for drugs that require rapid dissolution and absorption.
In addition to its role as a disintegrant, Crospovidone can also function as a stabilizer, binder, and filler in various pharmaceutical formulations. It improves the mechanical strength of tablets, enhances drug stability, and aids in achieving uniform drug content.
Furthermore, Crospovidone is generally recognized as safe (GRAS) by regulatory authorities and has a long history of safe use in pharmaceutical products. Its versatility and compatibility with various active ingredients make it an indispensable ingredient in the formulation of solid oral dosage forms.
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